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OpenStax: Free Microbiology Textbook

Free Microbiology Textbook from OpenStax

Table of Contents:

1. An Invisible World
1. Introduction
2. 1.1. What Our Ancestors Knew
3. 1.2. A Systematic Approach
4. 1.3. Types of Microorganisms
2. How We See the Invisible World
1. Introduction
2. 2.1. The Properties of Light
3. 2.2. Peering Into the Invisible World
4. 2.3. Instruments of Microscopy
5. 2.4. Staining Microscopic Specimens
3. The Cell
1. Introduction
2. 3.1. Spontaneous Generation
3. 3.2. Foundations of Modern Cell Theory
4. 3.3. Unique Characteristics of Prokaryotic Cells
5. 3.4. Unique Characteristics of Eukaryotic Cells
4. Prokaryotic Diversity
1. Introduction
2. 4.1. Prokaryote Habitats, Relationships, and Microbiomes
3. 4.2. Proteobacteria
4. 4.3. Nonproteobacteria Gram-Negative Bacteria and Phototrophic Bacteria
5. 4.4. Gram-Positive Bacteria
6. 4.5. Deeply Branching Bacteria
7. 4.6. Archaea
5. The Eukaryotes of Microbiology
1. Introduction
2. 5.1. Unicellular Eukaryotic Parasites
3. 5.2. Parasitic Helminths
4. 5.3. Fungi
5. 5.4. Algae
6. 5.5. Lichens
6. Acellular Pathogens
1. Introduction
2. 6.1. Viruses
3. 6.2. The Viral Life Cycle
4. 6.3. Isolation, Culture, and Identification of Viruses
5. 6.4. Viroids, Virusoids, and Prions
7. Microbial Biochemistry
1. Introduction
2. 7.1. Organic Molecules
3. 7.2. Carbohydrates
4. 7.3. Lipids
5. 7.4. Proteins
6. 7.5. Using Biochemistry to Identify Microorganisms
8. Microbial Metabolism
1. Introduction
2. 8.1. Energy, Matter, and Enzymes
3. 8.2. Catabolism of Carbohydrates
4. 8.3. Cellular Respiration
5. 8.4. Fermentation
6. 8.5. Catabolism of Lipids and Proteins
7. 8.6. Photosynthesis
8. 8.7. Biogeochemical Cycles
9. Microbial Growth
1. Introduction
2. 9.1. How Microbes Grow
3. 9.2. Oxygen Requirements for Microbial Growth
4. 9.3. The Effects of pH on Microbial Growth
5. 9.4. Temperature and Microbial Growth
6. 9.5. Other Environmental Conditions that Affect Growth
7. 9.6. Media Used for Bacterial Growth
10. Biochemistry of the Genome
1. Introduction
2. 10.1. Using Microbiology to Discover the Secrets of Life
3. 10.2. Structure and Function of DNA
4. 10.3. Structure and Function of RNA
5. 10.4. Structure and Function of Cellular Genomes
11. Mechanisms of Microbial Genetics
1. Introduction
2. 11.1. The Functions of Genetic Material
3. 11.2. DNA Replication
4. 11.3. RNA Transcription
5. 11.4. Protein Synthesis (Translation)
6. 11.5. Mutations
7. 11.6. How Asexual Prokaryotes Achieve Genetic Diversity
8. 11.7. Gene Regulation: Operon Theory
12. Modern Applications of Microbial Genetics
1. Introduction
2. 12.1. Microbes and the Tools of Genetic Engineering
3. 12.2. Visualizing and Characterizing DNA, RNA, and Protein
4. 12.3. Whole Genome Methods and Pharmaceutical Applications of Genetic Engineering
5. 12.4. Gene Therapy
13. Control of Microbial Growth
1. Introduction
2. 13.1. Controlling Microbial Growth
3. 13.2. Using Physical Methods to Control Microorganisms
4. 13.3. Using Chemicals to Control Microorganisms
5. 13.4. Testing the Effectiveness of Antiseptics and Disinfectants
14. Antimicrobial Drugs
1. Introduction
2. 14.1. History of Chemotherapy and Antimicrobial Discovery
3. 14.2. Fundamentals of Antimicrobial Chemotherapy
4. 14.3. Mechanisms of Antibacterial Drugs
5. 14.4. Mechanisms of Other Antimicrobial Drugs
6. 14.5. Drug Resistance
7. 14.6. Testing the Effectiveness of Antimicrobials
8. 14.7. Current Strategies for Antimicrobial Discovery
15. Microbial Mechanisms of Pathogenicity
1. Introduction
2. 15.1. Characteristics of Infectious Disease
3. 15.2. How Pathogens Cause Disease
4. 15.3. Virulence Factors of Bacterial and Viral Pathogens
5. 15.4. Virulence Factors of Eukaryotic Pathogens
16. Disease and Epidemiology
1. Introduction
2. 16.1. The Language of Epidemiologists
3. 16.2. Tracking Infectious Diseases
4. 16.3. Modes of Disease Transmission
5. 16.4. Global Public Health
17. Innate Nonspecific Host Defenses
1. Introduction
2. 17.1. Physical Defenses
3. 17.2. Chemical Defenses
4. 17.3. Cellular Defenses
5. 17.4. Pathogen Recognition and Phagocytosis
6. 17.5. Inflammation and Fever
18. Adaptive Specific Host Defenses
1. Introduction
2. 18.1. Overview of Specific Adaptive Immunity
3. 18.2. Major Histocompatibility Complexes and Antigen-Presenting Cells
4. 18.3. T Lymphocytes and Cellular Immunity
5. 18.4. B Lymphocytes and Humoral Immunity
6. 18.5. Vaccines
19. Diseases of the Immune System
1. Introduction
2. 19.1. Hypersensitivities
3. 19.2. Autoimmune Disorders
4. 19.3. Organ Transplantation and Rejection
5. 19.4. Immunodeficiency
6. 19.5. Cancer Immunobiology and Immunotherapy
20. Laboratory Analysis of the Immune Response
1. Introduction
2. 20.1. Polyclonal and Monoclonal Antibody Production
3. 20.2. Detecting Antigen-Antibody Complexes
4. 20.3. Agglutination Assays
5. 20.4. EIAs and ELISAs
6. 20.5. Fluorescent Antibody Techniques
21. Skin and Eye Infections
1. Introduction
2. 21.1. Anatomy and Normal Microbiota of the Skin and Eyes
3. 21.2. Bacterial Infections of the Skin and Eyes
4. 21.3. Viral Infections of the Skin and Eyes
5. 21.4. Mycoses of the Skin
6. 21.5. Protozoan and Helminthic Infections of the Skin and Eyes
22. Respiratory System Infections
1. Introduction
2. 22.1. Anatomy and Normal Microbiota of the Respiratory Tract
3. 22.2. Bacterial Infections of the Respiratory Tract
4. 22.3. Viral Infections of the Respiratory Tract
5. 22.4. Respiratory Mycoses
23. Urogenital System Infections
1. Introduction
2. 23.1. Anatomy and Normal Microbiota of the Urogenital Tract
3. 23.2. Bacterial Infections of the Urinary System
4. 23.3. Bacterial Infections of the Reproductive System
5. 23.4. Viral Infections of the Reproductive System
6. 23.5. Fungal Infections of the Reproductive System
7. 23.6. Protozoan Infections of the Urogenital System
24. Digestive System Infections
1. Introduction
2. 24.1. Anatomy and Normal Microbiota of the Digestive System
3. 24.2. Microbial Diseases of the Mouth and Oral Cavity
4. 24.3. Bacterial Infections of the Gastrointestinal Tract
5. 24.4. Viral Infections of the Gastrointestinal Tract
6. 24.5. Protozoan Infections of the Gastrointestinal Tract
7. 24.6. Helminthic Infections of the Gastrointestinal Tract
25. Circulatory and Lymphatic System Infections
1. Introduction
2. 25.1. Anatomy of the Circulatory and Lymphatic Systems
3. 25.2. Bacterial Infections of the Circulatory and Lymphatic Systems
4. 25.3. Viral Infections of the Circulatory and Lymphatic Systems
5. 25.4. Parasitic Infections of the Circulatory and Lymphatic Systems
26. Nervous System Infections
1. Introduction
2. 26.1. Anatomy of the Nervous System
3. 26.2. Bacterial Diseases of the Nervous System
4. 26.3. Acellular Diseases of the Nervous System
5. 26.4. Fungal and Parasitic Diseases of the Nervous System
Fundamentals of Physics and Chemistry Important to Microbiology
Mathematical Basics
Metabolic Pathways
Taxonomy of Clinically Relevant Microorganisms
Glossary

Supplemental OER Resources

Wccnet.edu

Open Educational Resources by Subject Disciplines Microbiology (wccnet.edu)

Textbooks

Microbiology
from Merlot II
Microbiology and Mycology
from African Virtual University
Microbiology
from OER Commons
Microbiology
from OpenStax
Bacterial Diseases in Humans
Open Microbiology textbooks
from Boundless

Course Resources

Approved Lists of Bacterial Names (Amended)
The Approved Lists of Bacterial Names was published in the International Journal of Systematic Bacteriology (IJSB 30: 225–420, 1980) and reprinted in book form to provide for the requirements of the Bacteriological Code (1976 Revision) in initiating a new starting date for bacterial nomenclature, 1 January 1980.
Microbiology
from Saylor Foundation
Microbiology Online Teachers Activities
Human Microbiome Project
"he NIH Common Fund Human Microbiome Project (HMP) was established with the mission of generating research resources enabling comprehensive characterization of the human microbiota and analysis of their role in human health and disease."

Open Source Journals

Morbidity and Mortality Weekly Report (MMWR)
The Morbidity and Mortality Weekly Report (MMWR) series is prepared by the Centers for Disease Control and Prevention (CDC).
Emerging Infectious Diseases e-journal
Emerging Infectious Diseases is a peer reviewed, open access journal published monthly by the Centers for Disease Control and Prevention (CDC).
Updates from the Field
A quarterly newsletter from CDC Center for Global Health, Division of Global Health Protection
mBio
As ASM’s first broad-scope, online-only, open-access journal, mBio offers rapid review and publication of the best research in microbiology and allied fields. The new journal continues ASM’s nonprofit publishing mission and is edited by scientists involved in active research.
PLOS Pathogens
PLOS Pathogens is an open-access, peer-reviewed journal published monthly by PLOS, a nonprofit organization.

Interactive Resources

MedMyst Microbiology games from Rice University
Microbiology Online Teachers Activities
CELLS Alive
CELLS alive represents 30 years of capturing film and computer-enhanced images of living cells and organisms for education and medical research. The site has been available continuously and updated annually since 1994 by James Sullivan.
Microbe Zoo
The Microbe Zoo is part of the DLC-ME project which was developed by the Comm Tech Lab and the Center for Microbial Ecology at Michigan State University.
Microbiology Online: Microbe Passports
Learn about microbes from this interactive site for students.

Microbes are very diverse they have an amazing variety of shapes and sizes and can exist in a wide range of habitats from hot springs to the icy wastes of Antarctica and inside the bodies of animals and plants. Microbes live in the soil and the rocks just think every time you walk on the ground you step on millions of microbes.
Predictive Microbiology Information Portal
The USDA Food Safety & Inspection Service (FSIS) and the USDA Agricultural Research Service (ARS) have joined together to produce the Predictive Microbiology Information Portal (PMIP). This portal is geared to assist food companies (large and small) in the use of predictive models, the appropriate application of models, and proper model interpretation. Our vision is that the PMIP will be the highway to the most comprehensive websites that brings together large and small food companies in contact with the information needed to aid in the production of the safest foods.

Leeuwenhoek

Lens On Leeuwenhoek

Watch the video on the life, times, and accomplishments of Antony van Leeuwenhoek (1632-1723), the Dutch scientist who used hand-made single-lens microscopes.